Sodium Level of Human Pancreatic Donors is a Critical Factor
نویسندگان
چکیده
of the City of Hope 11 12 13 *Corresponding author 14 15 Ismail H. Al-Abdullah 16 Department of Diabetes and Metabolic Diseases Research, 17 Beckman Research Institute of the City of Hope 18 1500 E. Duarte Rd, Duarte, CA 91010 19 Tel: 626-256-4673 Ext 60109 20 Fax: 626-256-8704 21 Email: [email protected] 22 23 24 25 Running title 26 27 Human islets from hypernatremic donors 28 29 30 31 32 33 34 Articles in PresS. Am J Physiol Endocrinol Metab (December 23, 2014). doi:10.1152/ajpendo.00443.2014
منابع مشابه
Sodium levels of human pancreatic donors are a critical factor for determination of islet efficacy and survival.
Organs from hypernatremia (elevated Na+) donors when used for transplantation have had dismal outcomes. However, islet isolation from hypernatremic donors for both transplantation and research applications has not yet been investigated. A retrospective analysis of in vivo and in vitro islet function studies was performed on islets isolated from hypernatremic (serum sodium levels≥160 meq/l) and ...
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